Akihide Ryo Selected Research

Interferons

1/2018	Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.
9/2017	Inhibitory effects of metachromin A on hepatitis B virus production via impairment of the viral promoter activity.
1/2016	Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity.
9/2015	Molecular dissection of HBV evasion from restriction factor tetherin: A new perspective for antiviral cell therapy.

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Akihide Ryo Research Topics

Disease

33	Infections 04/2022 - 01/2008
19	Neoplasms (Cancer) 01/2019 - 01/2003
11	Virus Diseases (Viral Diseases) 01/2022 - 01/2013
9	COVID-19 01/2022 - 01/2020
6	Breast Neoplasms (Breast Cancer) 01/2022 - 08/2002
5	Carcinogenesis 05/2012 - 08/2002
3	Reinfection 12/2021 - 01/2019
3	Adenocarcinoma of Lung 04/2016 - 11/2014
3	Alzheimer Disease (Alzheimer's Disease) 07/2015 - 12/2002
3	Prostatic Neoplasms (Prostate Cancer) 05/2012 - 01/2006
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 08/2022 - 01/2021
2	Hepatitis B 04/2022 - 01/2019
2	Severe Acute Respiratory Syndrome 02/2022 - 10/2020
2	Glioma (Gliomas) 01/2022 - 12/2007
2	Inflammation (Inflammations) 01/2021 - 04/2013
2	Carcinoma (Carcinomatosis) 01/2019 - 01/2006
2	Respiratory Tract Infections (Respiratory Tract Infection) 02/2017 - 01/2014
2	Body Weight (Weight, Body) 01/2016 - 02/2002
2	Hepatocellular Carcinoma (Hepatoma) 11/2015 - 12/2003
1	Dyspnea (Shortness of Breath) 08/2022
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Superinfection 01/2021
1	Coinfection 01/2021
1	Fever (Fevers) 01/2021
1	Lymphoma (Lymphomas) 12/2020
1	Human Influenza (Influenza) 10/2020
1	Starvation 01/2020

Drug/Important Bio-Agent (IBA)

20	Proteins (Proteins, Gene)FDA Link 04/2022 - 12/2002
12	Antiviral Agents (Antivirals)IBA 01/2022 - 09/2015
8	AntibodiesIBA 04/2022 - 12/2007
6	AntigensIBA 12/2021 - 06/2014
6	Biomarkers (Surrogate Marker)IBA 10/2021 - 06/2014
6	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 04/2009 - 01/2003
5	RNA (Ribonucleic Acid)IBA 01/2022 - 09/2013
5	EpitopesIBA 12/2021 - 10/2010
4	VaccinesIBA 08/2022 - 01/2013
4	Neutralizing AntibodiesIBA 02/2022 - 01/2019
4	Pharmaceutical PreparationsIBA 01/2022 - 09/2014
4	Peptides (Polypeptides)IBA 01/2019 - 10/2015
4	InterferonsIBA 01/2018 - 09/2015
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 09/2013
3	sodium-bile acid cotransporterIBA 01/2021 - 05/2014
3	Biological ProductsIBA 01/2020 - 09/2014
3	AutoantibodiesIBA 06/2014 - 08/2010
3	CytokinesIBA 09/2013 - 01/2008
2	Immunoglobulins (Immunoglobulin)IBA 04/2022 - 01/2020
2	Monoclonal AntibodiesIBA 04/2022 - 09/2020
2	pgRNAIBA 01/2022 - 01/2020
2	Nucleocapsid ProteinsIBA 01/2021 - 01/2020
2	Viral AntigensIBA 09/2020 - 09/2013
2	Sirolimus (Rapamycin)FDA Link 01/2020 - 01/2018
2	Serine (L-Serine)FDA Link 01/2019 - 07/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 09/2015
2	Messenger RNA (mRNA)IBA 08/2018 - 12/2003
2	NucleotidesIBA 09/2017 - 09/2013
2	Small Interfering RNA (siRNA)IBA 05/2012 - 12/2007
2	Cyclin D1IBA 03/2003 - 08/2002
1	2019-nCoV Vaccine mRNA-1273IBA 08/2022
1	Amino Acids FDA Link 04/2022
1	Membrane Proteins (Integral Membrane Proteins)IBA 04/2022
1	hepatitis B hyperimmune globulinIBA 04/2022
1	Therapeutic UsesIBA 01/2022
1	DNA Ligases (Ligases, DNA)IBA 01/2022
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2022
1	Hepatitis B e AntigensIBA 01/2022
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022
1	Single-Domain AntibodiesIBA 01/2022
1	Blood Proteins (Serum Proteins)IBA 10/2021
1	4- (4- dihexadecylaminostyryl)- N- methylpyridium (DiA)IBA 10/2021
1	ciglitazoneIBA 10/2021
1	Troglitazone (Rezulin)FDA Link 10/2021
1	2,4-thiazolidinedione (thiazolidinedione)IBA 10/2021
1	diphenyl (biphenyl)IBA 10/2021
1	LipopeptidesIBA 10/2021
1	ThiazolidinesIBA 10/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2021
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 01/2021
1	Janus Kinase InhibitorsIBA 01/2021
1	Oxygen (Dioxygen)IBA 01/2021
1	Interferon Type IIBA 01/2021
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2021
1	CaspasesIBA 01/2021
1	Macrophage Colony-Stimulating FactorIBA 01/2021
1	Peptide Hydrolases (Proteases)FDA Link 01/2021
1	Immunomodulating AgentsIBA 01/2021
1	HexokinaseIBA 12/2020
1	favipiravirIBA 10/2020
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	Mitogen-Activated Protein KinasesIBA 01/2020
1	Sirtuin 1IBA 01/2020

Therapy/Procedure

6	Therapeutics 04/2022 - 05/2010
2	Artificial Respiration (Mechanical Ventilation) 01/2021 - 01/2021
2	Prostatectomy (Retropubic Prostatectomy) 05/2012 - 01/2006
1	Molecular Targeted Therapy 01/2022
1	Extracorporeal Membrane Oxygenation 01/2021
1	Injections 01/2021
1	Drug Therapy (Chemotherapy) 12/2020
1	Immunotherapy 03/2020